Symptoms of thalassemia depend on the clinical severity of the disease and the therapies employed to treat it. Each child may experience symptoms differently. Patients with thalassemia trait generally do not experience any symptoms. Transfusion dependent thalassemia. The primary signs and symptoms of Cooley’s anemia in infancy, before

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Thalassemias are inherited blood disorders. If you have one, your body makes fewer healthy red blood cells and less hemoglobin. Hemoglobin is a protein that carries oxygen to the body. That leads to anemia. Thalassemias occur most often among people of

Mild anemia can make you feel tired. Mild anemia caused by alpha thalassemia trait might be mistaken for iron-deficiency anemia. Mild to Moderate Anemia and Other Signs and Symptoms. People who have beta thalassemia intermedia have mild to moderate anemia.

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Thalassemias can cause mild or severe anemia and other complications that can occur over time (such as iron overload). Symptoms of anemia include fatigue, difficulty breathing, dizziness, and a pale skin tone. Jaundice can be a symptom of thalassemia. The symptoms of thalassemia vary depending on the type of thalassemia. Symptoms will not show until the age of 6 months in most infants with beta Thalassemias are inherited blood disorders.

Symptoms of beta thalassemia include growth problems, bone abnormalities such as osteoporosis, and an enlarged spleen (the organ in the abdomen that plays a part in fighting infection). People with thalassemia can get too much iron in their bodies (iron overload), either from frequent blood transfusions or from the disease itself.

Thalassemia major can be fatal. People with alpha thalassemia major die in infancy.

Beta thalassemia is classified into two types depending on the severity of symptoms: thalassemia major (also known as Cooley’s anemia) and thalassemia intermedia. Of the two types, thalassemia major is more severe. The signs and symptoms of thalassemia major appear within the first 2 years of life. Children develop life-threatening anemia.

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India is the place of HbE and HbD variant mutations [19]. Clinically, HbE Beta-thalassemia vary from mild symptoms to transfusion dependent [9]. A rare HbQ Betathalassemia variant was reported in

Symptoms depend on the type and can vary from none to severe. Often there is mild to severe anemia (low red blood cells). Anemia can result in feeling tired and pale skin.
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Some of the major signs of thalassemia major include: Paleness Tamil Nadu; Kerala; with thalassemia is 25% when both parents are carriers and 0% when only one parent is a carrier.A person who has thalassemia trait may not have any symptoms at all or may Symptoms are not visible in people with thalassemia minor. Symptoms of thalassemia major may include bone deformities, enlargement of spleen and liver, heart problems, slow growth, delayed puberty, poor appetite, jaundice, anemia, etc,. Since thalassemia is passed from parents to children, it can't be prevented.

Thalassemia minor may cause mild anemia but usually produce no symptoms and is commonly overlooked; it should be differentiated from iron deficiency anemia. Cause of alpha thalassemia. The cause of alpha thalassemia is deletions involving the HBA1 and HBA2 genes. Other alpha thalassemia symptoms and signs.
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Symptoms depend on the type and can vary from none to severe. Often there is mild to severe anemia (low red blood cells).


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Non-transfusion dependent thalassemia The most common symptoms of non-transfusion dependent thalassemia are related to anemia: pale skin, lips, hands or under the eyelids increased heart rate (tachycardia) breathlessness, or difficulty catching a breath (dyspnea [danafarberbostonchildrens.org] Dyspnea or fatigue is reliably reported by the patients.

It is also called as minor thalassemia.

2. Mild thalassemia: These are the people suffering from alpha or beta-thalassemia minor. Their symptoms are: Mild anaemia; Tiredness due to anaemia. However, some of the people with alpha or beta thalassemia minor do not present with any symptoms. 3. Moderate thalassemia: These are the people suffering from beta-thalassemia intermedia. These people can present with the following symptoms: …

volunteers, Sickle cell disease (SCD) patients, a transfusion-dependent beta thalassemia major  second (FEV1) to forced vital capacity (FVC) <0.70 with the presence of symptoms. Christian Med Coll & Hosp CMC, Dept Pulm Med, Vellore, Tamil Nadu, India. Iran.;Ahvaz Jundishapur Univ Med Sci, Thalassemia & Hemoglobinopathy  Somali, Spanish, Swahili, Swedish, Tagalog, Tamil, Thai, Turkish, Ukrainian, Urdu, Uzbek, Vietnamese.

In this article, you'll learn what is Thalassemia. Further, it talks about the causes and symptoms of Thalassemia, along with the diagnosis, tests, and treatment of Thalassemia.