One of these environmental pollutants is nonylphenol ethoxylate (NP-9), also known as Tergitol, and its degradation product, nonylphenol (NP). The objective of this work was to determine the toxicity of NP and NP-9 in Caenorhabditis elegans. Wild-type L4 larvae were exposed to different concentrations of the surfactants to measure functional endpoints.

NPEs (nonylphenol ethoxylates) break down in the environment into nonylphenol (NP), one of the most notorious examples of persistent, bioaccumulative and toxic chemicals (PBTs). Widely recognized for extreme aquatic toxicity to fish and wildlife, NPEs and NP may also threaten the health of the developing fetus and young children.

These compounds frequently coexist in surface waters as the result of discharges from wastewater treatment plants that are inefficient at removing nonylphenolic compounds. NP is persistent in the aquatic environment, moderately bioaccumulative, and extremely toxic to aquatic organisms. NP has also been shown to exhibit estrogenic properties in in vitro and in vivo assays. NP’s main use is in the manufacture of NPEs.

These compounds frequently According to the classification provided by companies to ECHA in CLP notifications this substance is toxic to aquatic life with long lasting effects, causes serious eye damage, is harmful if swallowed and causes skin irritation. Acute toxicity - oral Reason for no classification: data conclusive but not sufficient for classification Acute toxicity - dermal Reason for no classification: data lacking Acute toxicity - inhalation Reason for no classification: data lacking Skin corrosion / irritation Hazard category: Skin Irrit. 2 Hazard statement: H315: Causes skin irritation. Acute toxicity tests using nonylphenol (NP), nonylphenol monoethoxylate (NP1EO), and nonylphenol diethoxylate (NP2EO) were conducted using the single chemicals and as binary and tertiary mixtures. These compounds frequently coexist in surface waters as the result of discharges from wastewater treatment plants that are inefficient at removing nonylphenolic compounds. alkyl chain, and a water soluble chain of 1-100 ethoxylate groups (1EO-100EO) [7]. The mostly used APEs, nonylphenol ethoxylates (NPEs) has an alkyl chain (C9H19, usually branched) and a chain of 9-10 ethoxylate groups (see Fig.1) [9].

23 Jul 2013 Nonylphenol and its ethoxylates (NP and NPEs) have been used for more than 40 years as detergents, emulsifiers, wetting agents and dispersing

Concerns have focussed on the potential for NP and NPE to cause feminisation in wildlife, such as fish exposed to NP and NPE contaminated effluents, as well as being a potential factor in the increasing incidence absence of other nonylphenol ethoxylate (NPE) degradation by-products, the toxicity, fate and behaviour of some of these (i.e. nonylphenol mono- and diethoxylates (NP1EO and NP2EO), mono- and di-nonylphenoxy carboxylic acids (NP1EC and NP2EC) have also been considered in this report. Nonylphenol and its ethoxylates (NP and NPEs) have been used for more than 40 years as detergents, emulsifiers, wetting agents and dispersing agents. From data obtained by Environment Canada, an estimated 18,000 tonnes of NP and NPEs were used in Canada in 1998.

2018-06-20 · The U.S. Environmental Protection Agency (EPA) expanded on June 12, 2018, the list of chemicals subject to reporting under the Emergency Planning and Community Right-to-Know Act (EPCRA) Toxics Release Inventory (TRI). The list now includes a category containing 13 nonylphenol ethoxylates (NPE).

Acute toxicity tests using nonylphenol (NP), nonylphenol monoethoxylate (NP1EO), and nonylphenol diethoxylate (NP2EO) were conducted using the single chemicals and as binary and tertiary mixtures. These compounds frequently coexist in surface waters as the result of discharges from wastewater treatment plants that are inefficient at removing nonylphenolic compounds. alkyl chain, and a water soluble chain of 1-100 ethoxylate groups (1EO-100EO) [7]. The mostly used APEs, nonylphenol ethoxylates (NPEs) has an alkyl chain (C9H19, usually branched) and a chain of 9-10 ethoxylate groups (see Fig.1) [9].

EPA is adding a nonylphenol ethoxylates (NPEs) category to the list of toxic 29 Mar 2021 NP is produced from the environmental degradation of nonylphenol ethoxylates, which are toxic nonylphenol metabolites [1, 2]. In addition, NP 1994, 1996). Due to the rapid biodegradation of the. alkylphenol ethoxylate, generating more toxic. metabolites with potential endocrine disruption,.

The acute toxicity of eleven detergents to fish: results of an interlaboratory excercise. nonipol 85 / nonipol 95 / nonoxinol / nonylphenol ethoxylate / nonylphenol ethylene oxide Practically non-toxic if swallowed (LD50 oral, rat > 2000 mg/kg). The present study seeks to elucidate the effect of an anionic sodium dodecyl sulfate (SDS) and a nonionic nonylphenol ethoxylate (NPEO), on ZnO NPs and the use of nonylphenol ethoxylates in industrial and institutional cleaning, earthworms is less than 10 or the long-term toxicity/exposure ratio is less than av J Sternbeck · 2011 · Citerat av 16 — their toxicity of persistence are PAHs, PCBs and PBDEs.
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Acute toxicity - oral Reason for no classification: data conclusive but not sufficient for classification Acute toxicity - dermal Reason for no classification: data lacking Acute toxicity - inhalation Reason for no classification: data lacking Skin corrosion / irritation Hazard category: Skin Irrit. 2 Hazard statement: H315: Causes skin irritation.

Due to its harmful effects on the environment, use and production of nonylphenol has been banned in European 2020-07-01 · Intergenerational toxicity of nonylphenol ethoxylate (NP-9) in Caenorhabditis elegans 1. Introduction. The reaction between ethylene oxide and nonylphenol (NP) is used to synthesize ethoxylated nonylphenol 2.

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NP is persistent in the aquatic environment, moderately bioaccumulative, and extremely toxic to aquatic organisms. NP has also been shown to exhibit estrogenic properties in in vitro and in vivo assays. NP’s main use is in the manufacture of NPEs.

Commercially produced nonylphenols are predominantly In sewage treatment plants, nonylphenol ethoxylate degrades into nonylphenol, which is found in river water and sediments as well as soil and groundwater. Nonylphenol photodegrades in sunlight, but its half-life in sediment is estimated to be more than 60 years. toxicity tests were collected from the littoral area of Sancti Petri (Gulf of Cadiz, southwest of Iberian Peninsula). Main physico-chemical and biological characteristics of the sea water used are summarized in Table I. Assessment of the Biodegradability and Ecotoxicty of a Nonylphenol Ethoxylate Surfactant in Littoral Waters NP’s acute (oral and dermal) toxicity is low.

27 Nov 2016 Nonylphenol Ethoxylates (NPE) are used in a wide variety of industrial applications and consumer products. NPEs, though less toxic than NP,

Persistence and degradability tion of NPEs occurs through the loss of ethoxylate (EO) groups, resulting in compounds that are more toxic, estrogenic, and environmentally persistent than the parent compounds (Environment Canada 2000). Primary biodeg-radation of NPEs in aquatic systems is fast, but the resul-tant products, nonylphenol monoethoxylate (NP1EO), Nonylphenol is highly toxic to aquatic organisms and has been found in natural waters. Because of nonylphenol's toxicity, chemical properties, and widespread use to make other chemicals, concerns have been raised over the potential risks to aquatic organisms from exposure to nonylphenol. of nonylphenol ethoxylates produces more toxic nonylphenol (NP) (Hano et al., 2009).

With decreasing length of the ethoxylate chain, bioaccumulation and toxicity of APEs increases [10]. Nonylphenol (NP) is the commercially most important member of the group of alkyl phenols. The term “nonylphenol” represents a large num-ber of isomeric compounds, varying in the point of attachment of the nonyl group to the phenol molecule, and in the degree of branching in the nonyl moiety. Commercially produced nonylphenols are predominantly In sewage treatment plants, nonylphenol ethoxylate degrades into nonylphenol, which is found in river water and sediments as well as soil and groundwater.